Using the 1-point correction, combined with a cutoff of 23.50, might be useful in ambulatory settings with a large turnout. The optimal cutoff for Nasreddine’s method was 23.50 (SE = 0.82 SP = 0.72 ). Nominal normative cutoffs (ES0 uLs) showed excellent specificity (SP range = 0.96–1.00 ) but poor sensitivity (SE range = 0.09–0.24 ). The original cutoff demonstrated high sensitivity (0.93 ) but low specificity (0.44 ) in discriminating between patients and controls. ROC curve analysis was performed to obtain optimal cutoffs. The diagnostic properties of the original cutoff (< 26) and normative cutoffs, namely, the upper limits (uLs) of equivalent scores (ES) 1, 2, and 3, were evaluated. Raw MoCA scores were adjusted according to the conventional 1-point correction (Nasreddine) and Italian norms (Conti, Santangelo, Aiello). Forty-five patients (24 PwMCI and 21 PwD) and 25 healthy controls were included. Retrospective data collection was performed for consecutive patients with clinically and biologically defined MCI and early dementia. In this phase II psychometric study on the Montreal cognitive assessment (MoCA), we tested the clinicometric properties of Italian norms for patients with mild cognitive impairment (PwMCI) and early dementia (PwD) and provided optimal cutoffs for diagnostic purposes.
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